Our fallopian tube epithelial scRNA-Seq paper is out:

  • Single-cell transcriptomics create a cellular atlas for benign fallopian tubes
  • A secretory-intermediate-ciliated path is projected for epithelial differentiation
  • PAX8, SOX17, and RUNX3 potentially drive fallopian epithelial differentiation
  • ‘‘Early secretory’’ epithelial cells are likely precursors for the majority of HGSCs

The work was a collaborative efforts between our lab and ovarian cancer biologists and clinicians (Dr. Kate Lawrenson lab) from Cedars Sinai Medical Center in Los Angeles.

Read the full article at: https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00292-8