Our joint paper with the Lambert lab defining the role of K17 and immune landscapes of head and neck cancer immunotherapy published in Clinical Cancer Research

Together with Paul Lambert’s lab, we identified the roles of K17 contribution in HNC immunotherapy and the immune landscape switch from “cold tumors” to “hot tumors” using scRNA-Seq. The work was led by Wei Wang in the Lambert lab in collaboration with others from UWCCC. Athena was the analyst of TCGA and scRNA-Seq data. Congrats!

Wang W, Lozar T, Golfinos AE, Lee D, Groski E, Ward-Shaw E, Hayes M, Kimple RJ, Hu R, Xu J, Keske A, Sondel PM, Fitzpatrick MB, Dinh HQ#, Lambert PF# (2022). Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade Clin Cancer Res 2022 May 27:OF1-OF16. doi: 10.1158/1078-0432.CCR-21-3039.